Inactivated polio vaccine is 10 years outdated in well being facilities with low adherence – 30.07.2022 – Information

10 years in the past, Zé Gotinha gained a robust ally to maintain polio away from Brazilian youngsters: the inactivated polio vaccine, whose intramuscular injection is taken into account more practical and safer than the well-known drops that eradicated the illness in Brazil and largely from the world. . Regardless of this, the decade-old anniversary of this vaccine within the Nationwide Program of Immunization (PNI) is being remembered this August with concern from researchers and well being authorities: whereas the illness is re-emerging in some elements of the world, polio vaccine protection in Brazil is additional away from the goal of 95% of protected youngsters.

Rowena Rosa

The inactivated polio vaccine was launched in 2012 with two doses, however was expanded to 3 doses in 2016. The PNI recommends that these be given at 2, 4 and 6 months of age, conferring immunity that solely strengthens at 15 months and at 15 months. 4 years, with oral vaccine drops.

Based on the Data System of the Nationwide Immunization Program (SI-PNI), the forecasted doses of the inactivated polio vaccine reached the final goal in 2015, when protection was 98.29% of youngsters born that yr.

After 2016, protection dropped to lower than 90%, reaching 84.19% in 2019. In 2020, the covid-19 pandemic affected the protection of a number of vaccines, and this immunizer reached solely 76.15% of infants. In 2021, which can nonetheless have information launched into the system, the share was beneath 70% for the primary time, at 69.9%.

If the nation share signifies a state of affairs the place three out of 10 youngsters haven’t been vaccinated, the state of affairs could also be worse in a regional studying. Whereas within the South the proportion is 79%, within the North it’s 61%. The state within the worst state of affairs, in keeping with the info panel, is Amapá, the place the share is barely 44% of infants immunized.

Agência Brasil reached out to the Ministry of Well being for touch upon the decline in polio vaccination protection and methods to reverse it, however didn’t hear again on the time of scripting this report. Able on the identical subject launched in February, the ministry stated it conducts communication actions all year long, not simply throughout vaccination campaigns, to strengthen data on the security and effectiveness of vaccines as a public well being measure.

polio-free zone

Brazil has not detected circumstances of poliomyelitis since 1989 and, in 1994, it acquired certification from the Pan American Well being Group (PAHO) as a zone free of untamed poliovirus circulation, together with your entire American continent.

International victory over the illness by vaccination has diminished the variety of circumstances worldwide from 350,000 in 1988 to 29 in 2018, in keeping with the World Well being Group. Wild poliovirus at this time circulates endemically solely in small areas of Central Asia, whereas in 1988 there was a world well being disaster with 125 endemic international locations.


Nevertheless, declining vaccination protection within the Americas has led the Pan American Well being Group (PAHO) to record Brazil and 7 different Latin American international locations as high-risk areas for the illness to return. The alert is available in a yr during which Malawi( , in Africa, once more reported a case of untamed poliovirus, and New York Metropolis, in the USA, reported a case of poliomyelitis with paralysis in an grownup who wouldn’t have traveled overseas.


Infectologist Luiza Helena Falleiros Arlant factors out that poliovirus an infection is commonly asymptomatic, however it may be severe and trigger irreversible and deadly paralysis as a result of, along with the limbs, poliomyelitis may paralyze the muscle tissue accountable for respiration. In these circumstances, the affected person’s survival might depend upon the usage of a respirator.

“There is just one option to stop polio, and that’s by vaccination. However with very low vaccination, there are extra inclined folks. If we have now virtually 3 million reside births per yr and if we have now a vaccination charge of 60%, we have now 40% of just about 3 million who haven’t been vaccinated”, warns the physician, who’s president of the Poliomyelitis Technical Chamber of the Ministry of Well being and member of the Brazilian Society of Immunizations (SBIm).

The infectologist exhibits that the three doses of the intramuscular vaccine depart youngsters protected towards the three serotypes of the poliovirus, whereas the drops solely immunize towards two of them. For fogeys who missed the time of this vaccine or delayed any of the three doses, the specialist recommends that they instantly return to the posts to proceed the vaccination program the place it was interrupted.

“If a baby has had a vaccine and hasn’t had a dose for 3 years, they need to get the second dose and two months later, get the third. Nobody begins the regime once more, they’ve to select up the place they left off. . And proceed with the intramuscular vaccine,” says the physician.


Luiza Helena Falleiros believes that the causes of the lower in vaccination protection are multifactorial. These vary from coaching staff at fundamental well being amenities to not miss vaccination alternatives and speaking about vaccination each time households go to posts to the residing situations of these accountable for youngsters who must be vaccinated.

“Locations should ideally open from 7:00 to 19:00, as a result of at this time you might be extra depending on work than ever and lacking a day of labor at this time means lacking a plate of meals on the desk. You may’t ask staff to cease incomes. cash to assist a household with the fundamentals to go to the well being heart. And but to get there and discover out that the vaccine has run out or that the vaccine hasn’t arrived they usually have to come back again the subsequent day.”

A researcher on the Institute of Immunobiological Expertise (Bio-Manguinhos/Fiocruz) for the reason that Seventies, Akira Homma participated within the work of structuring the manufacturing of polio vaccines in Brazil, which was decisive for the eradication of the illness. For him, the present vaccine protection could be very worrying, even in a rustic that’s self-sufficient within the manufacturing of intramuscular vaccine, in a partnership between Fiocruz and the pharmaceutical firm Sanofi.

“Once we used the attenuated virus vaccine to remove polio within the Nineteen Eighties, there have been nationwide vaccination days that concerned your entire Brazilian society and volunteers in hundreds of well being posts, vaccinating 18 million youngsters beneath 5 in two or three days”, he remembers. “I do not know if we might get that mobilization once more, as a result of the occasions are completely different, the priorities are completely different, however we have now to search for a message, as a result of the message that’s being despatched just isn’t reaching the inhabitants, it’s not. reaching the inhabitants”.

Polio eradication itself, in keeping with the scientist, brought about the inhabitants to lose their concern and curiosity within the illness, which was already a reason behind concern for households all over the world all through the twentieth century.

“At present’s inhabitants thinks it is already protected, but it surely’s not,” he says, who advocates that one other dose of inactivated polio vaccine be included within the childhood vaccination schedule and that an epidemiological survey be executed to search out out. how the immunity of adults who acquired solely the oral vaccine.

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